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Bioelectrical phase angle values in a clinical sample of ambulatory rehabilitation patients

December 31st, 2009 Posted in Measure Prognosis, Phase Angle, Prognosis, PrognostiCheck(R)

Phase angle is derived from the resistance(R) and reactance(Xc) measurements obtained from bioelectric impedance analysis (BIA) and is considered indicative of cellular health and membrane integrity.

PrognostiCheck® is a noninvasive measurement that uses a well-established vascular diagnostic technique to measure the values of resistance (R) and Reactance (Xc) and calculate phase angle . Phase angle is clearly associated with prognosis and survival as a powerful independent variable.

Here is an Abstract from a study conducted by Simon M Gunn that measured phase angle values of rehabilitation patients and compared them to reference values, measures of functional ability and serum C-reactive protein (CRP) levels to explore their utility as a clinical tool to monitor disease progression and treatment efficacy.

The study was conducted on 215 ambulatory rehabilitation patients aged 20 – 94 years. All participants had been hospitalized for a stroke, orthopedic or other condition resulting in a functional limitation. PhA was derived from BIA analysis and functional ability characterized using the Functional Independence Measure (FIM), timed up and go (TUG) and maximal quadriceps strength (MQS). Serum levels of CRP were also collected.

Stroke patients had the highest PhA (5.3°) followed by elective orthopedic surgery (5.0°) with the other group (4.3°) significantly lower than both previous categories (p < 0.001). Ambulatory rehabilitation patients' PhA values were dependent on age and sex (p < 0.001), lower than published age matched healthy reference values (p ≤ 0.05) and similar to other hospitalized or sick groups, but also higher than values reported in critically ill patients. Patients with CRP values less than 10 mg.L-1 had significantly (p = 0.005) higher mean PhA values. Furthermore, the highest functional status quartiles had significantly higher PhAs (p ≤ 0.04) for the FIM, MQS and TUG measures.

The results suggest that the phase angles of rehabilitation patients are between those of healthy individuals and seriously ill patients, thereby supporting claims that phase angle is indicative of general health status.

Phase angles are a potentially useful indicator of functional status in patients commencing an ambulatory rehabilitation program with a normal hydration status.

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This entry was posted on Thursday, December 31st, 2009 at 4:06 am and is filed under Measure Prognosis, Phase Angle, Prognosis, PrognostiCheck(R). You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

2 Responses to “Bioelectrical phase angle values in a clinical sample of ambulatory rehabilitation patients”

  1. Tweets that mention PrognostiCheck® » Blog Archive » Bioelectrical phase angle values in a clinical sample of ambulatory rehabilitation patients -- Topsy.com Says:

    December 31st, 2009 at 5:32 am

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  2. Marion Sasala Says:

    January 4th, 2010 at 10:31 pm

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